Global Cell Expansion Market Size by Trends, Segmentation, Top Key Players, Growth and Forecast To 2022-2031

Kenneth Research has evaluated the current market opportunities in Global Cell Expansion Market in the healthcare industry for the forecast period 2022-2031, which also includes the ongoing industry trends and innovations that will help industry players to attain their business targets. Apart from that, the inclusive data on market size, market share and forecast, growth opportunities and challenges for the market players, along with the worldwide analysis on regions- North America, Latin America, Europe, Asia Pacific and Middle East & Africa, has also been provided in the report.

In Q4 2021, U.S. current-account deficit widened stood at $224.8 billion. However, in Q1 22, CAD rose by 29.6%, reached to $291.4 billion, adding $66.6 billion to the gap. Export of good and services increased by $25.7 billion to reach $1.03 trillion in the first quarter of 2022. However, country’s goods and services deficit was $79.6 billion in June, down $5.3 billion from $84.9 billion in May, revised- reflecting some sight of relief. On the other hand, annual inflation rate in the country hit 8.5%. Energy CPI surged by 32.9% in July 2022, inflating the cost of logistic and signs to disrupt supply chain whilst electricity cost upsurged by 15.2%, highest since Feb 2006. Apart from that, In July 2022, existing US home sales declined 5.9% to 4.81 million (seasonally adjusted annual rate), the lowest since May of 2020 and below market expectations of 4.89 million. As mortgage rate touches highest at 6%, sales for houses declined for a sixth consecutive month. Global energy crises to remain at focal point impacting the economic activity in the U.S, pushing consumers to spend less on the products and services and save more.

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On the other hand, the worst is expected to be seen in the European countries, especially during 2022 winters. The energy and gas crises has already started grappling the region, wherein many Western European countries including Germany is looking for coal fired solutions to tackle the gas supply shortage created by Russian-Ukraine conflict.

Amidst global concerns, market players have started looking for safe investments by holding on to the new technology and product launches. Factors like currency translation, disruption in global supply chain, Anti-China sentiments brewing across the globe, slowdown in Chinese economy, inflated products prices, USD getting stronger every week, decreasing purchasing power and strict measures taken by central banks/institutions across the world to ensure less spending and more saving, could hit the demand for the product and service badly in near future.

The global cellular expansion market size in 2021 is estimated at USD 21 billion, and the compound annual growth rate (CAGR) is expected to be 10% during the forecast period 2022-2030. The increased use of automated solutions in cell expansion applications is one of the market drivers. The automated system minimizes the labor and costs incurred in the production of cell therapy products (CTP), gene therapy, and other biological agents; leading to a robust and reliable process. The major players involved in the development of CTP are expanding their product lines to meet the significant increase in global demand for these therapeutic products. For example, in March 2019, Lonza launched a comprehensive CellBio service portfolio, including cell line expansion and banking services. The solution is designed to meet the requirements of research applications and ultimately accelerate market revenue generation.

The paradigm shift to single-use systems (SUS) provides huge production advantages for CTP manufacturing. SUS eliminates the concerns of cross-contamination and crop contamination caused by improper sterilization. SUS can also produce CTP with high cell density and provide long-term cost savings. Therefore, the increase in SUS applications has promoted the development of CTP, thereby driving the growth of the market. Cell therapy is becoming more and more popular in the life science industry. Increased funding from private and government organizations and their initiatives to encourage the development of cell therapy have become market drivers. The International Stem Cell Research Association participates in determining funding opportunities related to stem cells in biomedical research applications. The replacement of serum and other incompatible reagents is essential to control the quality of products in CTP production. A number of studies have confirmed that the application of serum-free media controls the quality of the product. Researchers have also developed an optimization platform that combines high-throughput tools with evolution-based differential algorithms as an effective automated optimization strategy for serum-free culture formulations.

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Product Insights consumables led the product segment in 2020, accounting for 45% of the total share. It is expected to maintain its dominant position in the next few years. The availability of various commercial media and reagents dedicated to specific cell types contributes to the huge revenue share of this market segment. In addition, these products are convenient, ready-to-use, and are also available as serum-free formulations. Due to the automation of bioreactors and other expansion platforms to improve the efficiency of the cultivation process, the instrumentation sector is expected to record the fastest compound annual growth rate during the forecast period. The emergence of the automation platform standardizes the process, makes it easier to track the process, and reduces practice time; therefore, it can use the time of qualified personnel more effectively. Continued marketing and the introduction of automated planting equipment have also promoted revenue generation in the field of instruments. For example, in March 2019, Hitachi Co., Ltd. sold its automated large-scale cell culture equipment in Japan. This commercialization allows the manufacture of induced pluripotent stem cells for regenerative medicine applications. These efforts are expected to accelerate the generation of instrument revenue.

The mammalian cell segment has the highest revenue share in 2020, at 60%, and will maintain a dominant position during the forecast period because these culture systems are very popular in the production of complex protein therapies. This is because these systems have pharmacokinetic and functional relevance to the post-translational modification of the human body. Therefore, most biopharmaceuticals, including monoclonal antibodies, specific interferons, thrombolytics, and various therapeutic enzymes, are produced using these culture systems. Differentiated human cells account for a large portion of income because these cells perform specific functions in the body. Differentiated cells, such as fibroblasts, have gained immense importance in skin wound healing and skin bioengineering, thereby increasing the growth of fragments. In addition, the evaluation of 3D gingival fibroblast (GF) annulus as a viable and simple in vitro detection method for biomaterial testing has expanded its use rate. Human stem cells have received great attention and are expected to witness the fastest compound annual growth rate from 2020 to 2027. The exponential growth of research in this field and the great success of regenerative medicine are one of the key factors leading to faster growth. In addition, the implementation of automation, robotics and closed production systems in the production of clinical-grade mesenchymal stem cells is driving the development of this market segment.

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Application insight:
Due to the increase in biopharmaceutical approvals in recent years, the biopharmaceutical sector has the largest revenue share in 2020, at 25%. The entry of new biopharmaceutical companies and the proliferation of bioprocessing technologies have further promoted the development of biopharmaceuticals, which in turn promoted the expansion process that occurred during the biological production process. Commercially. Over the years, people have seen the introduction of alternative flat cell expansion technologies, such as compact multi-layer bioreactors. This is sufficient to meet the requirements of a closed system, limit the potential risks associated with pollution and maintain control of upstream production and large-scale unit production. Due to the expansion of cell-based vaccine production in recent years, the vaccine production segment is expected to show the fastest growth rate during the forecast period. The production of these vaccines provides a cost-effective manufacturing solution while speeding up the development process. The lady who produces clinical-grade mesenchymal stem cells promotes the development of this market segment.

End-use information:
The biotech and biopharmaceutical company sector had the largest share in 2020, at 45%, and will expand further at a significant growth rate. The expanding horizons of cell-based therapies in the healthcare industry is one of the main enabling factors for the vast majority of biopharmaceutical companies. For example, with the continuous improvement of injectable cell delivery systems for various clinical applications, cell-based therapies have gained great popularity in regenerative medicine. In addition, pharmaceutical and biopharmaceutical companies have also participated in acquisitions to expand their product portfolios. For example, in December 2019, Sartorius AG signed an agreement to acquire a 50% stake in Biological Industries, an Israeli cell culture manufacturer. This acquisition expands Sartorius’ cell culture product portfolio, especially in cell and gene therapy, regenerative medicine and other advanced therapies.

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Regional information:
North America accounted for the largest share in 2020, at 44%. The region will maintain its leading position in the next few years due to increased funding initiatives by government agencies that have accelerated the manufacturing and development of stem cells. Regenerative medicine and cell therapy products. This in turn has driven the demand for cell expansion platforms in the region. For example, in October 2019, the FDA and the Medical Technology Enterprise Consortium (MTEC) jointly provided $5.3 million in funding to the Southwest Research Institute (SwRI) (United States). SwRI invests these funds to multiply cells to develop personalized regenerative medicine. These investments have boosted revenue generation in the region. As various local pharmaceutical and biotech companies step up their efforts to develop and commercialize their cell therapies, the Asia-Pacific region is expected to experience the fastest growth during the forecast period. An Indian company Stempeutics Research Pvt. Ltd. formed an alliance with Kemwell Biopharma in July 2019 to commercialize its stem cell-based product Stempeucel. It is expected that these agreements will boost the sales of SMEs’ products.

Major companies and market share prospects:
Major market participants are taking various measures to expand their market share and maintain a competitive advantage in this field. In addition, they are also involved in cooperation and partnership models, product development, agreements, and business expansion strategies in undeveloped areas. For example, in June 2019, Demcon acquired a stake in cell therapy manufacturer Scinus Cell Expansion BV. Mother cell. The team is located in the Netherlands. This acquisition helped Scinus expand its business in the stem cell therapy market. Such growth measures are expected to increase the utilization rate of bioreactors used to cultivate stem cells, thereby promoting market growth. Some of the major players in the cell expansion market include: Thermo Fisher Scientific, Inc. GE Healthcare Corning, Inc. STEMCELL Technologies, Inc. Merck KGaAMiltenyi BiotecBecton, Dickinson and Company Terumo Bct, Inc. Sartorius AG Takara Bio, Inc. Trinova Biochem GmbHupcyte Technology Co., Ltd.

Market segments covered by the report:
The report forecasts global, regional and national revenue growth, and analyzes the latest industry trends in each sub-segment from 2022-2030. For the purpose of this research, Kenneth Research will report on the global cell expansion market based on products, cell types, applications, end-uses and regions: Product Outlook (Revenue, USD million, 2022-2030) Consumables, reagents, media, and serum Consumables, flasks and culture accessories, tissue culture flasks, bioreactor accessories, other culture flasks and accessories, instruments, automatic cell expansion systems, cell counters, centrifuges, bioreactors, other instruments, cell type perspective (revenue, million dollars, 2022-2030) mammalian human induction Stem cell (CS) CSAdulcid cell differentiation product development drug cost, 20 million USD for treatment of cancer research Stem cell research other end-use prospects (revenue, USD million, 2022-2030) Biopharmaceutical and biotechnology company research institution cell bank other.

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